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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1E
All Species:
21.21
Human Site:
S739
Identified Species:
46.67
UniProt:
Q15878
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15878
NP_000712.2
2313
261731
S739
A
K
E
V
S
P
M
S
A
P
N
M
P
S
I
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
S1194
A
K
E
V
A
E
V
S
P
M
S
A
A
N
I
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
S739
A
K
E
V
S
P
M
S
A
P
N
M
P
S
I
Dog
Lupus familis
XP_547425
2465
277756
S881
A
K
E
V
S
P
M
S
A
P
N
M
P
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q61290
2272
257217
S740
A
K
E
V
S
P
M
S
A
P
N
M
P
S
I
Rat
Rattus norvegicus
Q07652
2222
252098
S690
A
K
E
V
S
P
M
S
A
P
N
M
P
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
V661
W
A
S
L
S
N
L
V
A
S
L
L
N
S
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q2XVR3
1829
207718
G360
Y
T
S
Y
D
N
F
G
W
A
F
L
A
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
K382
R
R
N
A
A
K
R
K
K
L
K
S
L
G
K
Honey Bee
Apis mellifera
NP_001159376
1904
215872
M435
I
V
L
G
S
F
F
M
L
N
L
V
L
G
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
R495
L
S
V
L
R
A
L
R
L
L
R
I
F
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.8
95.8
90.7
N.A.
94.6
92.5
N.A.
N.A.
26.4
N.A.
20.4
N.A.
43.5
46.2
N.A.
39.5
Protein Similarity:
100
57.8
96.3
92
N.A.
95.8
93.8
N.A.
N.A.
41.9
N.A.
37.4
N.A.
55.8
57.8
N.A.
52.5
P-Site Identity:
100
40
100
100
N.A.
100
100
N.A.
N.A.
20
N.A.
0
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
66.6
100
100
N.A.
100
100
N.A.
N.A.
46.6
N.A.
6.6
N.A.
13.3
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
55
10
0
10
19
10
0
0
55
10
0
10
19
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
55
0
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
19
0
0
0
10
0
10
0
10
% F
% Gly:
0
0
0
10
0
0
0
10
0
0
0
0
0
19
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
55
% I
% Lys:
0
55
0
0
0
10
0
10
10
0
10
0
0
10
10
% K
% Leu:
10
0
10
19
0
0
19
0
19
19
19
19
19
10
0
% L
% Met:
0
0
0
0
0
0
46
10
0
10
0
46
0
0
10
% M
% Asn:
0
0
10
0
0
19
0
0
0
10
46
0
10
10
0
% N
% Pro:
0
0
0
0
0
46
0
0
10
46
0
0
46
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
10
0
0
10
0
10
10
0
0
10
0
0
0
0
% R
% Ser:
0
10
19
0
64
0
0
55
0
10
10
10
0
55
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
10
55
0
0
10
10
0
0
0
10
0
0
19
% V
% Trp:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _